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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRF1 All Species: 10
Human Site: T575 Identified Species: 16.92
UniProt: Q92994 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92994 NP_001510.2 677 73840 T575 R K L S R R R T P A S R S G A
Chimpanzee Pan troglodytes XP_510208 819 88957 T717 R K L S R R R T P A S R S G A
Rhesus Macaque Macaca mulatta XP_001098066 599 65136 A504 T P A S R S G A D P V T S V G
Dog Lupus familis XP_548005 637 70371 G542 K T P A S R S G A D P V T S V
Cat Felis silvestris
Mouse Mus musculus Q8CFK2 676 73781 R574 K K L S R R K R A T T R N S A
Rat Rattus norvegicus NP_001100231 686 74096 R584 K K L S R R K R A A T R N S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421405 681 75256 S580 K K L S R R K S I A S R N I A
Frog Xenopus laevis NP_001088063 660 73751 L562 D G I N S N Q L S R R K S A A
Zebra Danio Brachydanio rerio NP_956183 693 76806 R581 G R K R L T R R K K Q P N K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650616 662 73627 G567 Q P V I V E E G P V A S K S R
Honey Bee Apis mellifera XP_623775 648 73504 S553 I E I N N I A S S N K P I T S
Nematode Worm Caenorhab. elegans NP_495526 759 84015 E611 P K V N L K V E S A S P S T S
Sea Urchin Strong. purpuratus XP_794011 768 83924 R644 V N L S T P F R A G G V S Q G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29056 596 66888 K501 F L L E Q E S K R L K Q E A D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.3 86.4 82.7 N.A. 89.8 81.6 N.A. N.A. 78.1 72.5 65.9 N.A. 42.5 43.4 32.4 46.3
Protein Similarity: 100 80 87 85.9 N.A. 93.3 86 N.A. N.A. 87 84.7 77.6 N.A. 59.6 61.7 50 60.1
P-Site Identity: 100 100 20 6.6 N.A. 46.6 53.3 N.A. N.A. 60 13.3 6.6 N.A. 6.6 0 26.6 20
P-Site Similarity: 100 100 20 26.6 N.A. 73.3 80 N.A. N.A. 86.6 40 26.6 N.A. 26.6 33.3 53.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 0 8 8 29 36 8 0 0 15 43 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 8 8 0 0 0 0 8 % D
% Glu: 0 8 0 8 0 15 8 8 0 0 0 0 8 0 0 % E
% Phe: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 8 8 0 0 0 0 8 15 0 8 8 0 0 15 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 15 8 0 8 0 0 8 0 0 0 8 8 0 % I
% Lys: 29 43 8 0 0 8 22 8 8 8 15 8 8 8 0 % K
% Leu: 0 8 50 0 15 0 0 8 0 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 22 8 8 0 0 0 8 0 0 29 0 0 % N
% Pro: 8 15 8 0 0 8 0 0 22 8 8 22 0 0 0 % P
% Gln: 8 0 0 0 8 0 8 0 0 0 8 8 0 8 0 % Q
% Arg: 15 8 0 8 43 43 22 29 8 8 8 36 0 0 8 % R
% Ser: 0 0 0 50 15 8 15 15 22 0 29 8 43 29 22 % S
% Thr: 8 8 0 0 8 8 0 15 0 8 15 8 8 15 0 % T
% Val: 8 0 15 0 8 0 8 0 0 8 8 15 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _